Monistat 1 vs. Monistat 3 vs. Monistat 7

Monistat 1 vs. Monistat 3 vs. Monistat 7


Monistat 1 vs Monistat 3 Monistat 7

If you’re suffering from a vaginal yeast infection and looking for the most effective treatment, you may be wondering which of the Monistat vaginal cream applicators to choose.


In this article I’ll explain what is the difference between Monistat 1, Monistat 3 and Monistat 7 to help you choose the most suitable option for yourself and get rid of a yeast infection for good.


Monistat contains Miconazole, an antifungal compound that is very effective in treating vaginal yeast infections. You can buy Monistat with different concentrations of Miconazole and duration of treatment, have a look at this comparison chart:



 Duration of TreatmentAmount of Miconazole in 1 DoseWho is it for?

Monistat 1


1 day


1200 mg

Active women who don’t want to wait till bedtime to start treatment. Some users complain that 1 day option is not enough and they either don’t get better or their symptoms return within days.

Monistat 3


3 days


200 mg

Recommended for women who prefer a lower concentrated dosage and a longer treatment for better results.

Monistat 7


7 days


100 mg

Many women report that although the least concentrated, Monistat 7 is the most effective option when it comes to treating vaginal yeast infection.





What is Monistat 1?


Monistat 1 vs Monistat 3 Monistat 7

Monistat 1 consists of one does of 1200 mg of Miconazole nitrate and is designed for women who don’t want to wait till bedtime to start treatment. This ovule adheres to vaginal walls and does not leak, so you can insert it anytime during the day (or night) and go about your day as normal, you can even exercise! Your symptoms should ease from 3 to 7 days after inserting the ovule, if you see no improvement make sure you see your doctor.


It’s got a whopping 38% of one star reviews on Amazon. Due to high dosage of Miconazole, many women experience an allergic reaction with intense burning and pain. If you think you may be sensitive to Miconazole, choose Monistat 3 or Monistat 7 instead.


Ingredients: Miconazole Nitrate 1200 mg, Gelatin, Glycerin, Lecithin, Mineral Oil, Titanium Dioxide, White Petrolatum


What is Monistat 3?


Monistat 1 vs Monistat 3 vs Monistat 7

If you think you should use a less concentrated treatment, choose Monistat 3. With 200mg per dose and a three day treatment, there’s much lower risk of developing side effects such as vaginal burning. However, although it’s less concentrated, Monistat 3 has 34% of 1 star reviews on Amazon, which means that it may still be too strong for many women and cause unpleasant side effects.


If you don’t experience any improvement in your symptoms within 7 days from starting your treatment, seek advice of your healthcare professional.


Ingredients: Miconazole nitrate 4% (200 mg in each applicatorful), benzoic acid, cetyl alcohol, isopropyl myristate, polysorbate 60, potassium hydroxide, propylene glycol, purified water, stearyl alcohol


What is Monistat 7?


Monistat 1 vs Monistat 3 vs Monistat 7

Monistat 7 offers a low concentration of Miconazole nitrate making it a perfect option for who are sensitive to Miconazole. Women also report best results when using Monistat 7, with only 18% reporting vaginal burning or no improvement in symptoms. It contains 7 pre-filled applicators that are to be inserted into the vagina before bedtime for 7 consecutive nights. It’s very important to follow the treatment till the end for best results.


Based on all Monistat reviews I read, Monistat 7 is by far the most effective treatment option from the above Monists products.


Ingredients: Miconazole nitrate 2% (100 mg in each applicator), benzoic acid, cetyl alcohol, ispropyl myristate, polysorbate 60, potassium hydroxide, propylene glycol, purified water, stearyl alcohol.


Does Monistat produce any side effects?


Monistat rarely produces any side effects and if it does, they are usually mild. The possible side effects include:


  • mild or severe vaginal burning, stinging, swelling, itching, irritation and redness


  • appearance of pimple-like bumpsMonistat 1 vs Monistat 3 vs Monistat 7 (1)


  • pain, or flaking of the treated skin


  • headache


  • a frequent need to urinate


  • lower abdominal cramps


  • in case of a severe allergic reaction you may experience rash, hives, difficulty breathing, tightness in the chest, swelling of the mouth, face, lips, or tongue as well as fever or chills


You should never use Monistat if:


  • you’re allergic to any of its ingredients


  • your symptoms haven’t been diagnosed by a doctor as a yeast infection


  • you suffer from diabetis or AIDS, or you’re HIV positive


How to use Monistat?


Monistat 1 vs Monistat 3 vs Monistat 7 (1)

  • Insert one applicatorful into your vagina, preferably before going to bed for as many days as the label indicates.


  • Remember that Monistat is exclusively for vaginal use and you should avoid contact with your eyes, nose or mouth. If it happens, flush with cool water.


  • Before starting the treatment make sure you get diagnosed by a healthcare professional. Having your vaginal swabs analysed is the best option.


  • Avoid using tampons, douches, spermicides and lubricants while you are following a Monistat treatment until all of your symptoms disappear.


  • Avoid vaginal sexual intercourse while you’re following Monistat treatment.


  • Do not use in children younger than 12 years before consulting a doctor.


  • Monistat can carry risks to pregnant and breastfeeding women and their babies. Discuss you treatment options with your doctor.


What to do if Monistat doesn’t work?


Monistat 1 vs Monistat 3 vs Monistat 7

If you see no improvement after following a Monistat treatment, have your vaginal secretions analyzed to get properly diagnosed and rule out a different type of infection, such as bacterial vaginosis. It may also turn out that you are suffering from a vaginal yeast infection caused by a yeast strain difficult to treat with OTC medications. In that case I recommend Bona Dea Boric Acid Suppositories.


Boric acid is as a very effective remedy, even in stubborn and recurrent yeast infection treatment. You may experience a great relief in symptoms within hours from inserting a suppository. It’s a 100% natural treatment that carries a very low risk of side effects. If you look at ingredient list of any Monistat products, you’ll see they all contain potentially irritating compounds such as alcohol or propylene glycol, while Bona Dea suppositories’ only ingredient is pharmaceutical grade boric acid powder.





Monistat 1 vs Monistat 3 vs Monistat 7 (1)

All in all, if you’re suffering from a yeast infection, Monistat is a very effective and fairly safe treatment option. It rarely produces side effects and your symptoms should ease within 3 to 7 days. I cannot stress enough how important it is to get properly diagnosed by a health professional and preferably have your vaginal swabs analysed for accurate diagnosis. If you decide to take Monistat without consulting a doctor, you may delay treatment of a different type of infection, such as bacterial vaginosis, making it more difficult to treat.


If you prefer to treat you vaginal yeast infection with a natural remedy or you see that Monistat doesn’t work, I recommend trying boric acid suppositories, you can read more about them here.


I’d love to hear about your experiences. Have you ever used Monistat? Did it work? Please share your comments and questions in the comment section below.


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  • Hi, I totally agree with your advice. I tried all three Monistats and the only one that actually cured my yeast infection was Monistat 7. The other two didn’t give me any side effects but they didn’t work at all, so in future I’ll always go for Monistat 7.

    • Thanks for commenting Marge, it seems that the length of treatment and the low dosage of miconazole work better than a large dose applied only 1 – 3 times.

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