Probiotics for vaginal health: PurFem Suppositories Review

Probiotics for vaginal health: PurFem Suppositories Review


Purfem suppositories are vaginal ovules that contain two strains of probiotics that naturally occur in the vagina. The ovules help treat and prevent conditions related to a bacterial imbalance in the vagina, such as yeast infection or bacterial vaginosis.


They can be used from 12 years of age, to treat and prevent itching, burning, dryness, odor or unusual discharge, typical symptoms of vaginal yeast infection. You don’t need to remove it in the morning, as it dissolves in the vagina overnight and the contents keep working during the day to reestablish a healthy vaginal flora.


Rating: star-4star-4star-4star-4star-2




  • One box of Purfem contains 10 vaginal ovules


  • Ingredients: 1 billion CFU L. rhamnosus PBO1, 1 billion CFU L. gasseri EN-153471 (EB01), Lactitol Monohydrate, Maize starch, Gelatin, Xanthan Gum, Glucose (anhydrous), Magnesium Stearate, Titanium dioxide, Sucrose, Ascorbate and Citrates


  • It doesn’t need to be refrigerated, but should be kept between 15 and 20 °C (59 – 68 °F)


Where to buy: buy_button_amazon_com


How to use it?:


  • Insert one ovule overnight high into the vagina, make sure you wash your hands beforehand.


  • If you’re using Purfem to prevent a yeast infection, insert one ovule after your ovulation and after your period (depending on when you usually get your infections) for 4-6 days at bedtime.


  • When you’re on antibiotics, insert one ovule overnight for 6-8 days.


  • In order to treat or supplement treatment of a yeast infection, insert one ovule (followed by an antifungal vaginal suppository for best results) for 6-8 days overnight.




  • allergy to lactic acid bacteria or other ingredients


  • dairy allergy


Purfem Review


Side effects:


  • No side effects have been reported, but if you see that your symptoms don’t disappear after 8 days you should see the doctor because you may be suffering from a condition that needs different treatment.


  • If you forget to take your dose of Purfem, take your normal dose next time, without doubling the dose.




  • It’s got 70% of 5 and 4-star reviews on Amazon, which means that it’s helped many women solve their problems with yeast infections and bacterial vaginosis.


  • It’s got two strains of bacteria naturally found in the vagina and 10^9 CFU (colony forming units) is more than enough.


  • Seems to work best for bacterial vaginosis, according to reviewers.




  • What I don’t like about Purfem is the fact it contains glucose and sucrose (sugar). As we know, Candida thrives on sugar and providing food to the yeast directly down there may be counterproductive. However, after a lot of research, I see that all vaginal suppositories with probiotics contain some sort of sugar, so I assume the amount is so low, it won’t affect Candida growth in any way.


  • It’s got only two strains of friendly bacteria. Research shows that the more strains you provide, the more probable that the probiotic suppositories will work for you. It’s because women have got different vaginal probiotic trains depending on where they live, as well as their genes.


  • I don’t like the fact that there are no clinical studies described on Purfem website or anywhere else. Successful clinical studies make a brand more trustworthy. Having said that, there is a lot of research available about the strains used in Purfem, and they prove effective against vaginal yeast infections and bacterial vaginosis.


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  • It comes with only one applicator. You’ll have to disinfect it after each use. 10 disposable applicators would be much better.


  • It’s expensive!





There are cheaper products available on the market that are using the same probiotic strains and are supported by extensive clinical studies.


Some women say it didn’t work for them, it may be because the probiotic strains used in Purfem do not match their vaginal flora, and as there are only two strains, there is a chance they won’t match yours either.


The more probiotic strains in probiotic ovules, the higher the chance your vagina will be successfully colonized and protected against vaginal yeast infections. If you think that PurFem would work for you, you can buy it on Amazon.


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